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F.KapitzaC.et al (2012)

It is an episodic monoarthritis (polyarthritis in 10% of cases) Initially it was thought that gout happened due to excessive formation of uric acid but later on it became clear that it was mainly due to insufficient clearance by kidneys

Because it is a protein (a tripeptide), the body often sees it as food and tries to digest it into its individual amino acids

Antidiabetic activity of Berberis brandisiana is possibly mediated through modulation of insulin signaling pathway, inflammatory cytokines and adipocytokines in high fat diet and streptozotocin-administered rats