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Offers potential anti-inflammatory and neuroprotective effects
In the kidney, carnitine and butyrobetaine are reabsorbed efficiently by transport by a high affinity carnitine transporter termed the 'organic cation transporter novel 2 (OCTN2)', located in the renal brush border membrane and necessary for regulation of carnitine homeostasis
An early study compared excretion of gold through urine in 40 such patients with or without NAC, a single dose of 3000 mg by IV infusion over 6 hours, and found a 54% increase in excretion in the NAC group
REDEFINE-4 reported about 25.5% at 84 weeks in a head-to-head trial
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