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This includes the secretion of nitric oxide for vasodilation and endothelin-1 for vasoconstriction, which modulates vascular tension and diameter, directly influencing the balance of oxygen supply to meet tissue metabolic demands

Mutually exclusive HCRU endpoints included inpatient hospitalizations, emergency room (ER) visits, and outpatient medical services (including physician office visits, and other outpatient services)

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If the vial feels warm or if ice packs have completely melted into liquid with no remaining chill, contact the pharmacy before using the medication