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Generally, hypoxia itself can trigger angiogenesis by upregulating vascular endothelial growth factor (VEGF), hypoxia-inducible factor 1 (HIF1), T-cell intracellular antigen 1 (TIA1), eukaryotic translation initiation factor 2 (elF2), and thrombospondin (TSP1) [31]

This level of monitoring allows researchers to identify patterns that may indicate risk, even when side effects occur infrequently

GLP-1 therapies are not recommended in people with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2 (MEN2)