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Although genetically different, this CD56 bright NK cell population shared many similarities with a unique subset of CD56 superbright CD16 - decidual NK cells (dNK) deprived of cytotoxic activity, but involved in the modulation of decidual vascular growth during pregnancy through the secretion of angiogenic factors, such as VEGF, PlGF, and IL-8 (108)

And the early growth response 1 (egr-1) gene expression pattern, originally identified in skin wound healing, also appears in muscle and tendon repair work, suggesting a shared transcriptional response

The insets show the absolute values for all groups, including the controls

If lipedema progresses, the nodules can adhere to each other and the SAT, creating large, lumpy, painful masses