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Authors' Contributions Zijun Ma, Kaiqin Jin, and Mengmeng Yue contributed equally to this work

Most studies evaluating BPC-157, thymosin beta-4 derivatives, and related peptide agents are preclinical, employ heterogeneous dosing regimens, and report surrogate endpoints that do not translate directly to operative recovery or implant-based outcomes

Worth Noting CJC-1295 is most frequently studied in combination with Ipamorelin the two work through complementary pathways for synergistic GH release

Given that alcohol and drug abuse activate the same reward pathways involved in food intake, it is plausible that appetite-regulating peptides, such as GLP-1, exert their effects on brain regions associated with reward and addiction [20, 21]