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IGF-1 (Insulin-like Growth Factor 1): This is the primary marker used to confirm that the pituitary is successfully translating the GHRH signal into systemic growth hormone activity

Reassess every 2-4 weeks

Diagnostic steps: Review baseline and current measurements objectively (visual acuity, visual field, OCT imaging), ensure consistent daily peptide use without extended gaps, verify proper dosing and administration technique, confirm appropriate peptide choice for specific condition

Science 284(5418):13651368 Yoshimoto S et al (2013) Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome