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TIPE2 expression, which is regulated in a ROS-dependent manner, influences the balance between pro-tumoral and anti-tumoral activities by controlling the expression of genes like CEBP (pro-tumoral) and IFN- (anti-tumoral), driving the polarization of MDSCs [141]

The virus Virus Viruses are infectious, obligate intracellular parasites composed of a nucleic acid core surrounded by a protein capsid