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Description

found that plasma TMAO is positively associated with abundance of 12 bacterial genera in fecal, including three Bacteroidetes (Prevotella 7, Prevotella 2, an uncultured Prevotellaceae)

These include: Pain that does not improve after a few weeks

Split-dosing (taking a weekly dose in two or more smaller sub-weekly injections) changes the trough-to-peak ratio and can soften side effects at higher dose levels