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Here, we emulate a clinical trial that compares outcomes following initiation of GLP1-RA vs Dipeptidyl peptidase-4 inhibitors (DPP4i), as active comparators, in U.S

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1 Introduction Drugs that activate the glucagon-like peptide-1 (GLP-1) receptor are currently used clinically to treat type 2 diabetes mellitus (T2DM) and obesity ( The GLP-1 and GIP receptors (GLP-1R and GIPR, respectively) are closely related members of family B or the secretin class of G protein-coupled receptors (GPCRs) and share a high degree of sequence homology (Amgen, 2024)

Freezing the pen can change the medicines chemical structure, making it less effective