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Patients with Multiple Endocrine Neoplasia syndrome type 2, a genetic condition associated with increased risk of medullary thyroid carcinoma, should also avoid treatment with this medication

Never assume a new vial matches the old one

In the cardiovascular outcomes trial in adults, increases in total bilirubin greater than or equal to 3 times the upper limit of normal were observed in 0.3% (30/8585) of WEGOVY-treated patients versus 0.2% (14/8579) of placebo-treated patients

However, its important to note that neither medication is FDA-approved for weight loss, though healthcare providers may prescribe them off-label for this purpose when clinically appropriate