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On the other hand GPx3 is negatively correlated with MAPK oncogenic signaling pathway (94), which suggests a potential antitumor effect in thyroid cancer, while a decrease in GPx3 levels predisposes to an increase in the size of primary tumors and the number of metastatic lymph nodes (95, 96)

doi: 10.1186/s13048-022-01080-3 183 OchiaiAKurodaK

Dong CC, Yin XJ, Ma JY, Millecchia L, Wu ZX, et al: Effect of diesel exhaust particles on allergic reactions and airway responsiveness in ovalbumin-sensitized brown Norway rats