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Advances in clinical treatment of genetic disorders Individuals with sickle cell disease (SCD), thalassemia, or other anemias require long-term blood transfusions, often leading to iron overload that necessitates iron chelating therapy

Hypothalamic Fatty Acid Synthase (FAS) As indicated above, the intracellular levels of malonyl-CoA will decline as it is incorporated into de novo synthesized fatty acids via the action of FAS