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It means either the dose is wrong, the compound doesnt work for you, the product quality is poor, or the effect size is below what you can detect subjectively

However, recent studies have shown them to be important in modulating the innate immune response [105, 106, 107]

However, in LT + GSH treated plants eightfold, 18.3 fold and 1.3 fold increase in CAT activity was seen in G1C, G2C and G3C, respectively