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Upon treatment with polybia-MP1, the HLF cells displayed a distribution of 8% early apoptosis, 6% late apoptosis, 6% necrosis, and 80% viable cells

Specifically, Skovronsky noted a goal to deliver efficacy similar to injectable GLP-1 monotherapy in an easy-to-use daily pill. Skovronsky added that we expect results from up to six phase III studies by the end of 2026, and expect retatrutide can deliver deeper and more rapid weight-loss than existing obesity medicines, even more than tirzepatide, the prescription drug sold under brand names such as Mounjaro and Zepbound

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