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119,120 Carotid artery plaque burden, assessed by ultrasound, has been shown to predict risk of stroke, major adverse cardiovascular events, and death from any cause

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Moreover, a peripherally administered GLP-1R antagonist increased alcohol consumption while GLP-1R activation in the VTA was sufficient to reduce alcohol consumption in rats, indicating that the effect may be mediated by GLP-1R in the VTA (Shirazi et al., 2013)