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In many cases, there is only anecdotal knowledge on this subject from patients and therapists, which do not allow for a definite conclusion to be drawn

Common contraindications cited in the research-use community include: anyone with active or recent cancer (BPC-157 and TB-500 promote angiogenesis), people with Wilson's disease or other copper-metabolism disorders (GHK-Cu component), anyone pregnant or breastfeeding (no safety data), and athletes subject to WADA testing (BPC-157 and TB-500 are prohibited)

If you notice a significant increase in breakouts after starting a new supplement, bring it up with your provider but don't let a rare association deter you from correcting a genuine deficiency