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This consideration affects protocol design and subject selection in research settings

[23] The American College of Medical Toxicology and the American Academy of Clinical Toxicology warn the public that chelating drugs used in chelation therapy may have serious side effects, including liver and kidney damage, blood pressure changes, allergies and in some cases even death of the patient

A thorough understanding of how different metabolite fluxes intersect and influence each others impact on drug uptake and antibiotic resistance is needed in order to exploit the full potential of metabolic reprogramming and facilitate development of successful metabolism-based strategies to combat antibiotic resistance

Total glutathione and GSH levels were positively correlated (r2=0.669, P=8.181066