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Research also suggests benefits in reducing liver fat content in patients with non-alcoholic fatty liver disease/metabolic dysfunction-associated steatohepatitis (MASH), though these are not currently approved indications and represent areas of ongoing research

Although the number of included trials was limited, the results showed a consistent trend toward reduced AMS risk among subjects receiving antioxidant treatment, with a pooled effect suggesting an approximate 27% relative risk reduction

Persistent nausea lasting more than 48 hours after each injection

There are also emerging geographic and demographic disparities: studies have found lower GLP-1 fill rates among patients with obesity (37% fill rate) versus those with diabetes (4765% fill) ( [30] ), and lower fill rates for Hispanic and Black patients, reflecting both socioeconomic and coverage gaps ( [31] )