[5] While arginine is known to be beneficial to the mitochondria in neurotransmitters, [6] the issue is that it isn't very orally bioavailable [7,8] -- but L-citrulline works better than arginine itself in terms of increasing plasma arginine and total nitric oxide levels
early studies suggest favorable effects on inflammation
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Gene 533:469476 Alves E, Binienda Z, Carvalho F, Alves CJ, Fernandes E, de Lourdes Bastos M, Tavares MA, Summavielle T (2009) Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain