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Based on a large study conducted by researchers and published in The New England Journal of Medicine, the SELECT trial followed 17,604 adults with overweight or obesity and established cardiovascular disease

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Proc Natl Acad Sci 100(6):30653070 Begriche K, Igoudjil A, Pessayre D, Fromenty B (2006) Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it