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This is historically the first area of research on the molecule, consistent with its gastric origin and particularly important in the oral form

It binds to GLP-1 receptors in the brain, pancreas, and gut, producing three main effects: slowed gastric emptying (food stays in your stomach longer), reduced appetite signaling in the hypothalamus, and improved glucose-dependent insulin secretion

Now, these findings will be pondered at an advisory committee meeting, and then a final scheduling decision is expected in the first week of December

doi:10.1001/jama.2015.9676 Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S, et al