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Dose adjustment, including temporarily reducing the tirzepatide dose or slowing the titration schedule, may help if symptoms correlate with dose increases

00:13:50 Don Weinberger: So I remember in early twenty twenty four, uh FDA released a safety communication saying that they received several reports of suicidal ideation or action with GLP-1 agonists, but FDAs review of available evidence could not show a causal link, especially since the number of reports were really so limited

The advent of newer depigmenting molecules such as pycnogenol, orchid and marine algae extracts, cinnamic acid, soy, aloesin and Boswellia has offered more topical options

The answer isnt simple