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The exosome growth factors and signalling molecules normalise melanocyte behaviour across the entire treatment zone, producing a more even and lasting tone improvement than surface-only treatments

Astrocyte precursors do not appear to have the same benefit as mature astrocytes on nearby motor neurons in ALS rodents, indicating that a replacement of connectivity with motor neurons is needed rather than just trophic support ([37, 83]

From this shared extracellular microenvironment, GSH is cleaved by -glutamyl transpeptidase on the astrocytic plasma membrane to generate precursors for neuronal GSH synthesis