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17, 2025 /PRNewswire/ -- Novo Nordisk announced today that the US Food and Drug Administration (FDA) has approved Rybelsus , the only oral GLP-1 medication available, for reducing the risk of major adverse cardiovascular events (MACE) such as cardiovascular (CV) death, heart attack, or stroke in adults with type 2 diabetes who are at high risk for these events, whether they've had a prior CV event or not (primary and secondary prevention)

The primary endpoint in all studies was mean change in HbA 1c

However, patients are unlikely to see this immediately after starting semaglutide

Some of the common pro-inflammatory markers implicated across mental health disorders include IL-1, IL-6, IL-17, IL-1, and TNF- (93, 159)