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Dihydrolipoic acid (DHLA), the reduced form of lipoic acid, restores these antioxidants by reducing their oxidized forms, maintaining redox balance through antioxidant regeneration

In this comprehensive overview (see Methods and the search methodology in Supplementary Section 1), we aim to identify and describe pre-clinical, mechanistic and clinical studies on the effects of GLP-1RAs in cognitive and mental health disorders, and to provide a summary of available evidence and future perspectives

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In both cases the measured values are close to the end of the linear range of the respective probes with GRX1-roGFP2 being even slightly beyond its useful linear measurement range with an oxidation of 93%