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The sterol regulatory element-binding protein (SREBP) family of transcription factors plays a crucial role in lipid metabolism by regulating the expression of a series of enzymes required for lipid synthesis, and nuclear fragments of transcriptionally active SREBPs (nSREBPs) are unstable, degraded by the ubiquitin-proteasome pathway

For women, it shouldnt be above 20mc, and it can be administered twice daily

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For adults weighing below 50 kg, the dose of IV paracetamol is recommended at 15 mg/kg every 46 h with a maximum dose of 60 mg/kg/day