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Severe abdominal pain, particularly if it is persistent and located in the upper abdomen radiating to the back, requires urgent assessment to exclude pancreatitis, a rare but serious adverse effect of GLP-1 receptor agonists identified in the Wegovy SmPC

As part of this work we continue to monitor reports of adverse drug reactions through routine pharmacovigilance

These neuromodulatory patterns are dose-, device-, and sex-dependent, indicating that delivery method (standard spray versus breath-powered nebulizer) and hormonal milieu shape brain penetration and response

Over time, these changes may increase the risk of cavities