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Heart Health At high levels, homocysteine in the blood sticks to healthy cells, creating harmful proteins ( homocysteine-thiolactone and N-homocysteinylated proteins)

Principal feasibility and translation barriers Synthesizing evidence from completed trials, four major barriers prevent widespread clinical adoption of these advanced therapies

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In addition to metabolites of carbohydrate and lipid metabolism, amino acids (AAs) have emerged as putative biomarkers for the detection of joint diseases [8], and there are OA-related alterations in the profiles and metabolism of, for instance, glutamic acid and arginine family AAs [9]