Malfunctioning phagocytosis impairs the killing of bacteria that reach the lamina propria through the permeable epithelial barrier, which results in excessive Toll-like receptor stimulation, proinflammatory cytokine secretions, and activation of acquired immune responses, all of which significantly raise intestinal inflammatory reactions in genetically susceptible individuals who harbor mutations in the IBD-susceptibility gene(s) (Duboc et al., 2013)
Available from: Rajaobelina K, Helmer C, Vlayoudom-Cphise FL, Nov S, Farges B, Pupier E, et al
Never increase your dose without guidance from your prescribing provider
Clinical trials demonstrate that semaglutide monotherapy produces meaningful weight reductions, improved glycemic control, and cardiovascular benefits in patients with obesity and related conditions