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In the past, deficiencies of these vitamins have been directly correlated with several conditions: night blindness due to vitamin A deficiency, osteomalacia due to vitamin D deficiency, oxidative stress due to vitamin E deficiency, and excessive bleeding or hemorrhage due to vitamin K deficiency

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Microdosing titration with smaller dose increments Strategy B: Increase dosing frequency with reduced dose size This method involves administering smaller doses more frequently than once per week (e.g., every 34 days), which can help maintain more stable drug levels and potentially reduce side effects caused by peak concentrations