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Within the Wnt/-cateninVEGF axis, oridonin (ORI), an ent-kaurane-type diterpenoid isolated from the aerial parts of Rabdosia rubescens (Thunb.) Hara (Lamiaceae), has been shown to activate Wnt3a/-catenin signaling and upregulate VEGF expression, thereby promoting Type H vessel formation and enhancing bone density and structural regeneration (Yu et al., 2023, PMID: 36924567)

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Annals Romanian Soc Cell Biology 36163624 Cristofori F, Dargenio VN, Dargenio C, Miniello VL, Barone M, Francavilla R (2021) Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: a door to the body

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