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(PubMed) Kwok T, Wu Y, Lee J, et al

Several lifestyle, stress, and environmental factors encourage excessive free radical generation and oxidative stress, including: Air pollution, cigarette smoke, alcohol intake, toxins, bacterial, fungal, or viral infections, radiation, including extensive sun bathing, intense and lengthy exercise, which provoke tissue damage, antioxidant deficiency and finally enormous intake of antioxidants, such as vitamins C and E etc