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This was consistently visualized with different endothelial cell antigens, FVIII (involved in platelet adhesion and aggregation, present on endothelial cells of mature blood vessels) and CD34 (involved in leukocyte adhesion and endothelial cell migration during angiogenesis, present on capillary endothelial cells), as well as with VEGF presentation (main factor in angiogenesis, expressed on endothelial cells, mitogen for vascular endothelial cells)

For years, this made it an object of intense study for gut health and digestive tract issues, and the research in that area continues to be robust

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But its not a one-size-fits-all solutionand its not without its downsides