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95% CI, 1.62-11.29)yy6 Weight loss patients faced an even higher 7.64-fold increased risk (95% CI, 2.21-26.36) Cumulative NAION incidence of 8.9% for diabetic semaglutide users versus 1.8% for other medications 17 NAION events in diabetic semaglutide users compared to 6 in the control group 20 NAION events in weight loss semaglutide users versus only 3 in controls The research originated from clinical observations when three NAION patients presented within a short timeframe during summer 2023, all of whom were taking semaglutide

In a statement, they said pregnancy or intention to become pregnant were exclusion criteria in the companys trials with semaglutide for both obesity and type 2 diabetes

Final eligibility is decided by a prescriber after a full clinical assessment