5 years of Farxiga usage: Weight loss: 5-8 pounds (maximum amount achievable) Total costs: $30,000 to $36,000 (self-pay) or $1,500 to $6,000 (with insurance coverage) Side effects: Permanent UTIs, recurring yeast infections, increased dehydration risk Outcome after discontinuation: Weight gain back within 3 to 6 months Elimination of diabetes: 0% only possible through managing symptoms Frequency: Every day for years (and potentially a lifetime) Bariatric surgery (one-time surgical procedure): Weight loss: 60-80% of excess body weight Total costs: $15,000 to $25,000 (self-pay), or insurance coverage is often available Side effects: Recovery period post-surgery (2-4 weeks) Long-term outcome: Physiological change
For some individuals, even milder opioids can increase the risk of relapse
This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects
While the FDA has stated that current data do not demonstrate a causal link between GLP-1 receptor agonists and suicidal thoughts, healthcare providers should remain vigilant