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doi: 10.4158/EP.15.3.229 109 KishiyamaCMBurdickPLCobryECGageVLMesserLHMcFannK

Therefore, although DPP-4 inhibition reduces both fasting and postprandial glucose and HbA 1c levels, the effects are weaker than for GLP-1 receptor agonists, and they do not exhibit a body weight reduction effect, although they are body weight neutral

This decision directly impacts medspas offering weight loss services, as many have relied on compounding pharmacies to provide semaglutide-based treatments

According to NICE Technology Appraisal (TA875), Wegovy is recommended for adults with a BMI of at least 35 kg/m (or lower thresholds for certain ethnic groups) who have at least one weight-related comorbidity