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[1] [3] This means it activates both the GIP receptor and the GLP-1 receptor simultaneously, making it pharmacologically distinct from traditional GLP-1 agonists

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Of course when they gain it all back which easily 90% will do ( and we would see that if somebody had the balls to measure with DEXAs 2,3 or 4 years after cessation) of course their comorbidities will return