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When used for type 2 diabetes, the dosing recommendations are: Immediate-release tablet: 500 mg once or twice daily, or 850 mg once daily Extended-release tablet: 500 mg1,000 mg once daily For weight loss, PCOS, gestational diabetes, or other off-label uses of metformin, the dosage varies but most people start at 500 mg

Eligibility is specific: adults with a BMI of 27 or higher who have experienced a heart attack, stroke, or peripheral arterial disease

Experts warn that as with any other "trend", peptides must be combined with a healthy diet and exercise to produce long-lasting effects

You may notice bleeding especially while passing stools