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Pain from these tumors may be confined to the tumor site or spread across the region Lumbar plexus tumor can lead to weakness, numbness, walking difficulties, and severe shooting pain in the back, due to compression of the nerve If the sacral plexus nerve of the lower back is affected, it can cause back pain, alteration in bowel movements and bowel control, alteration in urinary bladder control, etc

Journal of Pharmaceutical Sciences 105 , 417430, doi:10.1016/j.xphs.2015.11.002 (2016)