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In 1987, it was shown that infusion of GLP-1 into healthy, fasted volunteers caused insulin levels to rise, with a subsequent reduction in plasma glucose

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Apoyo conductual: Considere trabajar con un dietista registrado o participar en programas de modificacin conductual

However, in the Diabetes Prevention Programme, which randomised 3,234 individuals with IGT to intensive lifestyle modification, metformin or placebo, there was no difference in the incidence of cardiovascular events between the treatment groups over 3 years [48]