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Another study investigated the neuroprotective effects of Cyn in an in vitro neurodegenerative model (SH-SY5Y neuroblastoma cells induced with 6-hydroxydopamine hydrobromide [6-OHDA]) and reported that Cyn suppressed 6-OHDA-induced mitochondrial and nuclear damage, although the levels of ROS were not affected

The 4mg dose remains a reasonable target for those who can't tolerate higher doses while still producing clinically significant weight loss

E -values, following VanderWeele and Dings approach, estimated the minimum strength of association needed by unmeasured confounders to fully explain observed associations, addressing potential biases from unmeasured confounding 53,54

Key active ingredients include Sodium