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CaladaDVianelloDGiampieriESalaCCastellaniGde GraafAet alThe role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: a systems biology approach

It promotes resolution of inflammation by shifting macrophage activity from a pro-inflammatory (M1) phenotype toward a reparative (M2) phenotype, thereby effectively reducing fibrosis and promoting enhanced tissue regeneration [11, 23, 26, 50]

Localization, colocalization, and plasticity of corticotropin-releasing factor immunoreactivity in rat brain