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Evaluation of antioxidant status and oxidative stress markers in follicular fluid for human in vitro fertilization outcome

Notably, five overexpressed GST isozymes reduced the typical accumulation of ROS, which suggested that these isozymes could glutathionylate ROS-generating enzymes with GSH, thus inhibiting superoxide and hydrogen peroxide in both mitochondria and the cytoplasm [50]

The Cu2+ ion is coordinated by the histidine imidazole nitrogen and the N-terminal amino group of glycine, forming a specific metal-peptide complex