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As a proxy for heavy smoking (binary variable), we used diagnosis codes related to lung diseases highly associated with tobacco exposure along with diagnosis codes related to nicotine or tobacco, previous use of medications for the treatment of tobacco dependence, and initiation of drugs for obstructive airway disease after the age of 40

doi: 10.1016/j.trac.2010.02.015 50 BouchezAVauchelPPrinoSDimitrovK

Sermorelin is generally very well tolerated when used appropriately, but women should understand that its not a more is better therapy, Knight says

PT-141 is FDA-approved specifically for premenopausal women with hypoactive sexual desire disorder (HSDD)