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The inner mitochondrial membrane is strictly impermeable to activated long-chain fatty acids (LCFAs), which possess 12 to 20 carbon atoms and represent the body's most dense and efficient source of potential energy

10.1073/pnas.1401861111 47 KimbleJ.CrittendenS

Given the widespread use of GLP-1 medications for weight management and diabetes, the findings could have significant public health implications

doi: 10.3390/ijms232314631, Summary Keywords GLP-1/GIP dual agonist, metabolic regulation, obesity, obstructive sleep apnea, tirzepatide Citation Fang Q, Zhu Y, Rao M and Liu P (2026) GLP-1/GIP dual agonist tirzepatide in obstructive sleep apnea syndrome: mechanisms, evidence, and clinical perspectives