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Following 1:1 propensity score matching, both the GLP-1 RA user and non-user groups included 183,264 patients

79 In diabetes, the sugar metabolite methylglyoxal could be responsible for increased oxidative stress, synthesis of AGE product with a simultaneous enhancement of inflammation, and a decline in NO (nitric oxide) availability in the endothelium

Many users observe markedly reduced cravings and smaller meal portions within weeks of starting therapy

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