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259679, the Innovation-Oriented Research Programme on Genomics (SenterNovem IGE01014 and IGE05007), the Centre for Medical Systems Biology and the Netherlands Consortium for Healthy Ageing (grant 050-060-810), all in the framework of the Netherlands Genomics Initiative, Netherlands Organization for Scientific Research (NWO), BBMRI-NL, a research infrastructure financed by the Dutch government (NWO 184.021.007 and 184.033.111), the VOILA Consortium (ZonMW 457001001) and the Netherlands Consortium of Dementia Cohorts (NCDC) (ZonMW Memorabel 73305095005)