In people without disorders of biotin metabolism, doses of up to 5 mg/day (5,000 g) for two years were not associated with adverse effects (66)
Y., Osorio-Vasquez, V., Rodrick, T., Gonzlez-Baerga, D., Zhao, E., Yokoyama, Y., Simeone, D
A new, federally funded retrospective study led by Johns Hopkins Medicine strongly suggests that semaglutide and other GLP-1 RAs did not statistically change the risk of developing neovascular age-related macular degeneration (NVAMD)-a fast-progressing, blinding condition that is caused by uncontrolled, abnormal blood vessel growth in the back of the eye-in adults with type 2 diabetes without a prior history of GLP-1 use
If an active person is not careful to replace the lost fluids and nutrients, they could develop leg cramps