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It acts as a mild preservative, but it cannot prevent oxidation entirely

Relationship between gst yp induction and hepatocyte proliferation in rats treated with phase ii drug metabolizing enzyme inducers

The production of ROS is mainly secondary to enzymatic reactions involved in the respiratory chain, activity of cytochrome p-450, synthesis of prostaglandins and phagocytosis (Pizzino et al., 2017)

Another possibility is that obesity could lower serum vitamin B12 levels through decreased dietary intake or absorption, increased catabolism, and sequestration in adipose tissue, or changes in the gut microbiota profiles which could affect the metabolism of vitamin B12